Hi iklink,
Yes, you can use the part in an AC coupled system (DC blocked) as well as a DC coupled system (AC + DC). Note, in an AC coupled system you will be limited to 7dBm max RF power, if you need more you will have to apply a DC bias through the switches of up to 0.5V to raise the RF power handling to 16dBm. Please have a look at the follow app note for more details about biasing the switch and other useful information.
http://www.analog.com/static/imported-files/application_notes/AN_952.pdf
Eric.